Groundbreaking discovery in memory research confirmed the extract PTI-00703 from the Amazon, cat’s claw plant as a strong inhibitor, and a reducing agent against amyloid Plaques and neuro-fibrillary bundles

Edmonds, Washington (ots/PRNewswire) – Scientific Reports recently published a landmark research work, the immediate effective importance to the health of the brain and loss of memory in old age has brains. The work with the title „the Amazon rain forest plant Uncaria tomentosa (Cat’s claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles“ identified claw the extract PTI-00703 for the cat, a Plant from the rain forest of the Amazon, as a powerful natural solution to inhibit and reduce the accumulation of beta-amyloid Plaque and neuro-fibrillar Bundles consisting of Tau Protein, which is the main reason of memory loss in old age.

Dr. Snow and his Team have found that the main polyphenols in the PTI-00703-cat’s claw (also known as proanthocyanidins) are for the strong anti-inflammatory and anti-hypertensive effect on amyloid Plaques and neuro-fibrillary bundles of responsible and have for the first time found out, how these specific polyphenols in improved health of the brain. This is the first publication in which the mechanism is to be decrypted, such as the Beta-Sheets of the proteins amyloid Plaques and neuro-fibrillary Bundles by special polyphenols disintegrate in a newly discovered, natural plant extract.

The research, which is available at the following Link,
https://www.nature.com/articles/s41598-019-38645-0 that was from Dr.
Alan Snow, a world-renowned researcher in the field of aging in the brain and Alzheimer’s disease written. To be promoted to the research, which extended over a period of ten years, and the claw has a lot of important results about the effects and mechanisms of action of PTI-00703-cat, a natural plant-based inhibitors of amyloid Plaques and neuro-fibrillary Bundles, which, until now, never been reported, days were ladies and gentlemen from eight different institutions notice involved.

Among the identified Highlights the efficiency of, inter alia:

* The components of the main Polyphenols of PTI-00703-cat’s claw enter the blood very rapidly (within minutes) in the
Brain.

* Small-molecular-weight polyphenol components of PTI-00703-cat’s claw
then bind to the beta-amyloid Protein in Plaques and the Tau Protein in the neuro-fibrillar Bundles.

* These components form a wedge, the Beta-Sheet secondary structure of the beta-amyloid protein in the fibrils
the Plaques and the Tau-Protein filaments in the neuro-fibrillar Bundle in a special way and completely breaks, so that they immediately disintegrate into almost amorphous, non-fibrillar Material.

* The Microglia of the brain to eliminate the toxic Material and transport it from the brain.

* The reduction of the Plaque load in the brain by 50-60 % over a period of 3 months of leads in the case of plaque-image-transgenic mice to a significant (50-60 %) improvement in short-term memory.

* The ingredients of PTI-00703-cat’s claw a also led to
significant reduction of inflammation in the brain.

„This research proves that the complex Code, the role of strong polyphenols, in particular, PTI-00703-cat’s claw, for the health of the brain play has finally been decrypted. Humanity (including me) has tried for centuries to solve this biological puzzle, and to create a drug, the amyloid Plaques and neuro-fibrillary bundles of reduce is capable of, while the key was to do this all the time in nature,“ said lead author Dr. Alan Snow.

Dr. Snow continued: „This is a huge leap in the field of brain health, the aging of the brain and the research in relation to age-related memory loss. For the coming year, a placebo-controlled, double-planned blind study on humans and I’m sure that this study will confirm our findings from this research work. All who value the protection of memory, should be looking forward to this pioneering work. Who would have thought that the key lies in a Plant from the Depths of the Amazon?“

Information about Dr. Alan Snow, Senior researcher and author

Dr. Alan Snow is one of the world’s most well-known sizes in the range of the research to the aging of the brain and Alzheimer’s disease. He is a former adjunct Professor in the research in the area of pathology at the University of Washington in Seattle, where he was a more than 10 year as a project team leader in the research center for Alzheimer’s disease. Dr. Snow has published several publications on amyloid Plaques and neuro-fibrillary bundles, the first to the presence of heparan sulfate Proteoglycans (HSPGs) in the case of Alzheimer’s disease-prion diseases discovered and has demonstrated that HSPGs in the case of the Emergence of Alzheimer’s disease and as a host of other amyloid disorders play an important role. He is the inventor of 340 issued patents, a carrier of a LEAPS award from the Michael J. Fox Foundation for Parkinson’s research and has received 18 grants from the National institutes of Health, including support for the identification of new inhibitors of Plaques and neuro-fibrillary Bundles. Dr. Snow has been more than research for 30 years in the areas of aging of the brain, memory loss, amyloid Plaques and neuro-fibrillary bundles and is currently the founder and CEO of the Edmonds in the US state of Washington-based Cognitive Clarity Inc. .

Claire Swift
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