EQS-News: Peer-reviewed publication by Marinomed Biotech AG and Friedrich-Alexander-University Erlangen-Nürnberg reconfirms broad virus-blocking effectiveness of iota-carrageenan

EQS-News: Marinomed Biotech AG / Key word(s): Scientific publication
Peer-reviewed publication by Marinomed Biotech AG and Friedrich-Alexander-University Erlangen-Nürnberg reconfirms broad virus-blocking effectiveness of
iota-carrageenan

13.07.2023 / 07:45 CET/CEST
The issuer is solely responsible for the content of this announcement.

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Peer-reviewed publication by Marinomed Biotech AG and Friedrich-Alexander-University Erlangen-Nürnberg reconfirms broad virus-blocking effectiveness of
iota-carrageenan

• Joint publication of virologists in the peer-reviewed journal Nutraceuticals demonstrates effectiveness of iota-carrageenan (Carragelose) against SARS-CoV-2
Omicron variants BA.1, BA.2 and BA.5
• Results demonstrate superiority of iota-carrageenan compared to other virus-blocking carrageenans in inhibiting the replication of a wide range of respiratory
viruses
• Protective barrier provided by iota-carrageenan is applicable as safe prophylaxis and early treatment of viral respiratory infections and might help fight
future pandemics

Korneuburg, Austria, 13 July 2023 – Marinomed Biotech AG (VSE:MARI) and scientists from Friedrich-Alexander University Erlangen-Nürnberg and University Hospital
Tuebingen published new data on the virus-blocking effectiveness of iota-carrageenan. The study was published in the international, peer-reviewed journal
[1]Nutraceuticals and showed that iota-carrageenan significantly inhibits viral replication in human lung cells infected with SARS-CoV-2 OM variants of concern
(VoC) BA.1, BA.2 and BA.5 isolated from infected patients.

The authors investigated the virus-blocking properties of three different types of carrageenan (iota, kappa and lambda). While all carrageenan types had a
virus-blocking effect, iota-carrageenan showed superior inhibition of all tested viral subtypes. These results are in line with previously published [2]data on the
virus-blocking effectiveness of iota-carrageenan against the original SARS-CoV-2 virus strain, its VoCs Alpha, Beta, Gamma and Delta as well as against other
respiratory viruses like rhinovirus A and B, influenza A virus or respiratory syncytial virus (RSV). This suggests that therapeutics containing iota-carrageenan
can be an effective add-on to vaccinations to protect people from future pandemics caused by respiratory viruses.

Prof. Dr. Ulrich Schubert, Professor at the Institute of Clinical and Molecular Virology at the Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany, and
principal investigator of the study, commented: “Even though the COVID-19 pandemic has fortunately evolved into an endemic, SARS-CoV-2 remains with us as a new
respiratory virus and will likely become part of the usual cold season. From this point of view, broadly active, safe and easy-to-use measures such as the use of
nasal sprays, throat sprays or lozenges containing iota-carrageenan are a useful addition to the prevention and early treatment of viral respiratory infections.
The results of this study confirm once more that iota-carrageenan is applicable for prophylaxis and early treatment of SARS-CoV-2 infections, independent of the
current and potential future variants.”

Dr. Eva Prieschl-Grassauer, Chief Scientific Officer of Marinomed and co-author of the study, added: “The lessons learned from the pandemic moved treatment of
viral respiratory infections into the focus of pharmaceutical activity. As severe respiratory viruses remain a public health threat, therapeutics that help prevent
both infection and transmission, regardless of the virus type, are essential. Products containing iota-carrageenan can be a valuable contribution to this. This is
confirmed by our newly published data that join a growing number of publications proving the virus-blocking effects of iota-carrageenan. Nasal sprays and further
products containing iota-carrageenan are available without prescription in numerous countries around the world and approved for the use in children as young as one
year.”

About Carragelose®

Carragelose® is a sulfated polymer from red seaweed and a unique, broadly active virus-blocking compound. It is known as a gentle, effective, and safe prevention
and treatment of various viral respiratory infections. Several clinical and preclinical studies have shown that Carragelose® forms a protective layer on the mucosa
that prevents viruses from infecting cells. Laboratory and clinical data have demonstrated that Carragelose® can also inhibit the spreading of
SARS-CoV-2.[3][1],[4][2] Marinomed is the holder of the IP rights and has licensed Carragelose® for marketing in Europe, North America, Australia, and parts of
Asia and Latin America. Marinomed’s portfolio of Carragelose®-containing nasal sprays and oral products can be accessed at
[5] https://www.carragelose.com/en/portfolio/launched-products, scientific publications on Carragelose® at [6] https://www.carragelose.com/en/publications.

About Marinomed Biotech AG

Marinomed Biotech AG is an Austrian, science-based biotech company with a growing development pipeline and globally marketed therapeutics. The Company develops
innovative patent-protected products in the therapeutic areas immunology and virology based on the platform Marinosolv® and the virus-blocking activity of
Carragelose®. The Marinosolv® technology improves the solubility and bioavailability of hardly soluble compounds and is used to develop new therapeutics for
autoreactive immune disorders. The virology segment includes Carragelose®-based over-the-counter (OTC) products to prevent and treat respiratory viral infections
that are partnered in more than 40 countries. The Company is headquartered in Korneuburg, Austria, and is listed on the prime market of the Vienna Stock Exchange
(VSE:MARI). For further information, please visit: [7] https://www.marinomed.com.

For further inquiries contact:

Marinomed Biotech AG International Media Contact
PR: Lucia Ziegler Metrum Communications: Eva Ruppnig
T: +43 2262 90300 158 T: +43 664 4065744
E-Mail: [8]pr@marinomed.com E-Mail: [10]marinomed@metrum.at
IR: Stephanie Kniep  
T: +43 2262 90300 226
E-Mail: [9]ir@marinomed.com
 

Disclaimer

This press release contains forward-looking statements, which are based on current views, expectations and projections of the management of Marinomed Biotech AG
about future events. These forward-looking statements are subject to risks, uncertainties and assumptions that could cause actual results, performance or events to
differ materially from those described in, or expressed or implied by, such statements. The current views, expectations and projections of the management of
Marinomed Biotech AG may be identified by the context of such statements or words such as “anticipate,” “believe”, “estimate”, “expect”, “intend”, “plan”,
“project” and “target”. Forward-looking statements are only valid as of the date they are made and Marinomed Biotech AG does not assume any obligation to update,
review or revise any forward-looking statements contained in this press release whether as a result of new information, future developments or otherwise.
Marinomed, Marinosolv® and Carragelose® are registered trademarks of Marinomed Biotech AG. These trademarks may be owned or licensed in select locations only.

[11]^[1]  [12]https://www.dovepress.com/efficacy-of-a-nasal-spray-containing-iota-carrageenan-in-the-postexpos-peer-reviewed-fulltext-article-IJGM

[13]^[2]
 [14]https://www.marinomed.com/en/news/marinomed-biotech-ag-shares-positive-clinical-trial-results-for-iota-carrageenan-nasal-spray-in-the-prevention-of-covid-19-1

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13.07.2023 CET/CEST This Corporate News was distributed by EQS Group AG. www.eqs.com

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Language: English
Company: Marinomed Biotech AG
Hovengasse 25
2100 Korneuburg
Austria
Phone: +43 2262 90300
E-mail: office@marinomed.com
Internet: www.marinomed.com
ISIN: ATMARINOMED6
WKN: A2N9MM
Listed: Regulated Unofficial Market in Berlin, Dusseldorf, Frankfurt,
Munich, Stuttgart, Tradegate Exchange; Vienna Stock Exchange
(Official Market)
EQS News ID: 1678809

 
End of News EQS News Service

1678809  13.07.2023 CET/CEST

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